1. Mouse Alopecia Areata Models: An Array of Data on Mechanisms and Genetics 
John P. Sundberg, Lloyd E. King 
Journal of Investigative Dermatology Symposium Proceedings 
Volume 8, Issue 2, Pages (October 2003)
DOI: /j x
Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions

2. Figure 1
Antigen presenting cells (APCs, Langerhans Cells) with B7.1 and B7.2 surface ligands carry antigenic epitope(s) from the donor skin to draining lymph nodes. These activate lymphocytes with CD28 ligands. Those with CD44.var.10 surface receptors migrate to the skin homing in on anagen stage hair follicles to induce AA at sites distant to the skin graft. Monoclonal antibodies that block these receptors and ligands prevent alopecia areata.
Journal of Investigative Dermatology Symposium Proceedings 2003 8, DOI: ( /j x)
Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions