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Postimplantation morphologic changes of glutaraldehyde-fixed porcine aortic roots and risk of aneurysm and rupture  Tirone E. David, MD, Susan Armstrong,

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Presentation on theme: "Postimplantation morphologic changes of glutaraldehyde-fixed porcine aortic roots and risk of aneurysm and rupture  Tirone E. David, MD, Susan Armstrong,"— Presentation transcript:

1 Postimplantation morphologic changes of glutaraldehyde-fixed porcine aortic roots and risk of aneurysm and rupture  Tirone E. David, MD, Susan Armstrong, MSc, Manjula Maganti, MSc, Jagdish Butany, MD, Christopher M. Feindel, MD, Joanne Bos, RN  The Journal of Thoracic and Cardiovascular Surgery  Volume 137, Issue 1, Pages (January 2009) DOI: /j.jtcvs Copyright © 2009 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 Survival after aortic root replacement with porcine aortic roots. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2009 The American Association for Thoracic Surgery Terms and Conditions

3 Figure 2 Freedom from reoperation.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2009 The American Association for Thoracic Surgery Terms and Conditions

4 Figure 3 Freedom from severe aortic insufficiency.
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2009 The American Association for Thoracic Surgery Terms and Conditions

5 Figure 4 Changes in diameter of the aortic sinuses during follow-up. Zero indicates early postoperative diameters. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2009 The American Association for Thoracic Surgery Terms and Conditions

6 Figure 5 Changes in diameter in 20 patients with aortic sinuses of greater than 40 mm during follow-up. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2009 The American Association for Thoracic Surgery Terms and Conditions

7 Figure 6 Left, This longitudinal section from an explanted Freestyle bioprosthesis shows the porcine aorta (P), the host aorta (H), and connective tissue deposited between the two. The porcine aorta shows multifocal destruction (“digestion”) of tissue and replacement with connective tissue (∗). Inflammatory cells are still present in the junctional areas between the porcine aortic media and the connective tissue (arrows). A thick layer of host tissue reaction is seen overlying the anastomosis of the porcine aorta with the host aorta. (Movat Pentachrome stain; original magnification, ×16.) Right, A section of porcine aorta (P) from an explanted Freestyle valve showing destruction of the media (arrows) and replacement by loose connective tissue. Inflammatory cells are seen in the junctional area. (Movat Pentachrome stain; original magnification ×100). The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2009 The American Association for Thoracic Surgery Terms and Conditions

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