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Low-dose inhaled fluticasone propionate versus oral zafirlukast in the treatment of persistent asthma  Eugene R. Bleecker, MDa, Michael J. Welch, MDb,

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Presentation on theme: "Low-dose inhaled fluticasone propionate versus oral zafirlukast in the treatment of persistent asthma  Eugene R. Bleecker, MDa, Michael J. Welch, MDb,"— Presentation transcript:

1 Low-dose inhaled fluticasone propionate versus oral zafirlukast in the treatment of persistent asthma  Eugene R. Bleecker, MDa, Michael J. Welch, MDb, Steven F. Weinstein, MDc, Christopher Kalberg, PhDd, Marty Johnson, MSd, Lisa Edwards, PhDd, Kathleen A. Rickard, MDd  Journal of Allergy and Clinical Immunology  Volume 105, Issue 6, Pages (June 2000) DOI: /mai Copyright © 2000 Mosby, Inc. Terms and Conditions

2 Fig. 1 Mean change from baseline in FEV1 over 12 weeks and at end point. Asterisk, P < .001 versus zafirlukast. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2000 Mosby, Inc. Terms and Conditions

3 Fig. 2 Mean change from baseline at end point in morning PEF stratified by severity of airway obstruction. Asterisk, P ≤ .001 versus zafirlukast. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2000 Mosby, Inc. Terms and Conditions

4 Fig. 3 The percentage of symptom-free days over 12 weeks of treatment and at end point. Asterisk, P ≤ .021 versus zafirlukast. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2000 Mosby, Inc. Terms and Conditions

5 Fig. 4 Rescue albuterol use over 12 weeks of treatment and at end point. Asterisk, P < .001 versus zafirlukast. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2000 Mosby, Inc. Terms and Conditions

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