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a) Cumulative count and b) percent cumulative use of the different pulmonary function test (PFT) measures as longitudinal outcomes for systemic sclerosis-associated interstitial lung disease progression. a) Cumulative count and b) percent cumulative use of the different pulmonary function test (PFT) measures as longitudinal outcomes for systemic sclerosis-associated interstitial lung disease progression. For each year, percent cumulative use was calculated by dividing the cumulative use of each PFT measure by the cumulative number of published articles. No distinctions were made between absolute and % predicted PFT values. All variations of diffusing capacity of the lung for carbon monoxide (DLCO) were grouped together into one all-encompassing DLCO measure. Other PFTs included measures of forced expiratory flow over the mid-half of forced vital capacity (FVC), forced expiratory volume in 1 s (FEV1)/FVC, FEV1/vital capacity (VC), functional residual capacity, residual volume and total lung capacity (TLC). Melissa Caron et al. Eur Respir Rev 2018;27:170102 ©2018 by European Respiratory Society
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