1. BAK oligomerization in cells treated by UV is
Cell death independent
Caspase independent
Cytochrome c release independent
Caspase-2 independent
All of above

2. How did the authors identify Mcl-1
Biochemical purification
By guessing
By both biochemical purification and candidate testing
By genetic cloning
None of above

3. Mcl-1 elimination upon UV irradiation is due to
Blocking of protein synthesis
Accelerated protein degradation
Both blocking of protein synthesis and accelerated protein degradation
An unknown reason
None of above

4. Overexpression of Bcl-xL can
A. Inhibit UV-induced Bax translocation to mitochondria B. Inhibit UV-induced Mcl-1 degradation C. Inhibit UV-induced Bax oligomerization on mitochondria D. Inhibit UV-induced Bak translocation to mitochondria D. None of the above

5. Based on the paper, the role of Bcl-xL in UV-induced apoptosis is
A. to promote Mcl-1 degradation B. to help translocation of Bax to mitochondria C. to mediate Bax oligomerization on mitochondria D. not understood E. to mediate cytochrome c release