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Cryptic No Longer: Arrays of CLASP1 TOG Domains

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Presentation on theme: "Cryptic No Longer: Arrays of CLASP1 TOG Domains"— Presentation transcript:

1 Cryptic No Longer: Arrays of CLASP1 TOG Domains
Jeremy D. Wilbur, Rebecca Heald  Structure  Volume 21, Issue 6, Pages (June 2013) DOI: /j.str Copyright © 2013 Elsevier Ltd Terms and Conditions

2 Figure 1 CLASP TOG Domain 2 Architecture May Confer Unique Activity to CLASPs Compared to Other TOG Domain-Containing Proteins (A) TOG or cryptic TOG (TOG-like [TOGL]) domains found in human CLASP1. (B) TOG2 adopts a bent architecture and is stabilized by an N-terminal helix (α2N). (C) TOG2 may stabilize the depolymerizing MT by binding curved tubulin dimers in curling protofilaments. Structure  , DOI: ( /j.str ) Copyright © 2013 Elsevier Ltd Terms and Conditions

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