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Published byRosaline Morgan Carroll Modified over 5 years ago
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Harnessing the potential of epigenetic therapies for childhood acute myeloid leukemia
Ashley A. Newcombe, Brenda E.S. Gibson, Karen Keeshan Experimental Hematology Volume 63, Pages 1-11 (July 2018) DOI: /j.exphem Copyright © 2018 ISEH – Society for Hematology and Stem Cells Terms and Conditions
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Figure 1 Epigenetic therapies in acute myeloid leukemia. DNA methylation, histone modifications, and associated epigenetic regulators. Epigenetic inhibitors are highlighted in red. C = cytosine; 5mC=5-methylcytosine; 5hmC=5-hydroxymethylcytosine; DNMT=DNA methyltransferase; HDAC=histone deacetylase; IDH=isocitrate dehydrogenase; 2KG=2-ketoglutarate; αKG=α-ketoglutarate; Ac=acetylation. Experimental Hematology , 1-11DOI: ( /j.exphem ) Copyright © 2018 ISEH – Society for Hematology and Stem Cells Terms and Conditions
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