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Volume 60, Issue 6, Pages (June 2014)

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1 Volume 60, Issue 6, Pages 1310-1324 (June 2014)
Bacterial infections in cirrhosis: A position statement based on the EASL Special Conference 2013  Rajiv Jalan, Javier Fernandez, Reiner Wiest, Bernd Schnabl, Richard Moreau, Paolo Angeli, Vanessa Stadlbauer, Thierry Gustot, Mauro Bernardi, Rafael Canton, Agustin Albillos, Frank Lammert, Alexander Wilmer, Rajeshwar Mookerjee, Jordi Vila, Rita Garcia-Martinez, Julia Wendon, José Such, Juan Cordoba, Arun Sanyal, Guadalupe Garcia-Tsao, Vicente Arroyo, Andrew Burroughs, Pere Ginès  Journal of Hepatology  Volume 60, Issue 6, Pages (June 2014) DOI: /j.jhep Copyright © 2014 European Association for the Study of the Liver Terms and Conditions

2 Fig. 1 Mortality rate caused by bacterial infections in cirrhosis in the last decades. 1-month and 1-year mortality rates were higher before than after 2000, although differences were not statistically significant. Modified from [6]. Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © 2014 European Association for the Study of the Liver Terms and Conditions

3 Fig. 2 Pathogenesis of bacterial infections in cirrhosis. The risk of bacterial infection in cirrhosis is due to multiple factors that include liver dysfunction, portosystemic shunting, gut dysbiosis, increased bacterial translocation, cirrhosis-associated immune dysfunction (AID) and genetic factors. Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © 2014 European Association for the Study of the Liver Terms and Conditions

4 Fig. 3 Pathophysiological basis of acute on chronic liver failure and end-organ dysfunction in cirrhosis precipitated by infection. Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © 2014 European Association for the Study of the Liver Terms and Conditions

5 Journal of Hepatology 2014 60, 1310-1324DOI: (10. 1016/j. jhep. 2014
Copyright © 2014 European Association for the Study of the Liver Terms and Conditions


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