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Efficacy and duration of antistaphylococcal activity comparing three antibiotics bonded to Dacron vascular grafts with a collagen release system  Arun.

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Presentation on theme: "Efficacy and duration of antistaphylococcal activity comparing three antibiotics bonded to Dacron vascular grafts with a collagen release system  Arun."— Presentation transcript:

1 Efficacy and duration of antistaphylococcal activity comparing three antibiotics bonded to Dacron vascular grafts with a collagen release system  Arun Chervu, MD, Wesley S. Moore, MD, Milos Chvapil, MD, PhD, DSc, Theodore Henderson, BS  Journal of Vascular Surgery  Volume 13, Issue 6, Pages (June 1991) DOI: / (91) Copyright © 1991 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

2 Fig. 1 This compares the area of bacterial inhibition on a blood agar plate as a function of time that the graft has been soaking in solution before testing. The curves for chloramphenicol palmitate bonded with collagen, amikacin bonded with collagen, rifampin in a blood preclot, and rifampin bonded to grafts with collagen are compared. The best and longest result occurred with rifampin bonded with collagen. This was statistically better and for a longer duration than the other two antibiotics bonded with collagen or rifampin mixed in a blood preclot. Journal of Vascular Surgery  , DOI: ( / (91) ) Copyright © 1991 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions


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