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Extent of lymphadenectomy is associated with oncological efficacy of sublobar resection for lung cancer ≤2 cm  Brendon M. Stiles, MD, Jialin Mao, MD,

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Presentation on theme: "Extent of lymphadenectomy is associated with oncological efficacy of sublobar resection for lung cancer ≤2 cm  Brendon M. Stiles, MD, Jialin Mao, MD,"— Presentation transcript:

1 Extent of lymphadenectomy is associated with oncological efficacy of sublobar resection for lung cancer ≤2 cm  Brendon M. Stiles, MD, Jialin Mao, MD, Sebron Harrison, MD, Benjamin Lee, MD, Jeffrey L. Port, MD, Art Sedrakyan, MD, Nasser K. Altorki, MD  The Journal of Thoracic and Cardiovascular Surgery  Volume 157, Issue 6, Pages e1 (June 2019) DOI: /j.jtcvs Copyright © Terms and Conditions

2 Figure 1 Identification of patients for inclusion from the Surveillance, Epidemiology and End Results Program-Medicare database between 2007 and SLR, Sublobar resection. The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

3 Figure 2 Survival increased with increasing numbers of lymph nodes examined. Using node counts as cutpoints and piecewise cox regression, a cutpoint of 9 was selected as the most discriminatory based on the lowest Akaike information criterion. The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

4 Figure 3 Overall survival and cancer-specific survival following lobectomy and sublobar resection (SLR) for lung cancer with tumor size ≤2 cm among Medicare beneficiaries. A and B, Before propensity-score matching. C and D, After propensity-score matching. Matching conducted without considering lymph nodes examined. The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

5 Figure 4 Subgroup analysis of overall survival and cancer-specific survival following lobectomy and sublobar resection (SLR) for lung cancer with tumor size ≤2 cm among Medicare beneficiaries after propensity-score matching. A and B, Patients with at least 1 lymph node examined. C and D, Patients with at least 9 lymph nodes examined. The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

6 After matching, survival of sublobar resection (red) is equivalent to lobectomy (blue).
The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

7 The Journal of Thoracic and Cardiovascular Surgery 2019 157, 2454-2465
The Journal of Thoracic and Cardiovascular Surgery  , e1DOI: ( /j.jtcvs ) Copyright © Terms and Conditions

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