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Symmetry Breaking in C. elegans: Another Gift from the Sperm

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1 Symmetry Breaking in C. elegans: Another Gift from the Sperm
Daniel J. Marston, Bob Goldstein  Developmental Cell  Volume 11, Issue 3, Pages (September 2006) DOI: /j.devcel Copyright © 2006 Elsevier Inc. Terms and Conditions

2 Figure 1 Polarization of C. elegans by Sperm-Contributed Cues
Fertilization (A) imparts two sperm-derived components that are essential for polarization (B), CYK-4 (purple) and the pair of centrosomes (orange) derived from the single sperm centrosome. The sperm nucleus (gray) is dispensable for polarization. Polarization signals lead to contraction of the actomyosin network (red), which carries the anterior PAR proteins (green) (C). This allows access to the cortex for the posterior PAR complex (blue) (D). (E) diagrams the regulatory pathway involved in this process. Developmental Cell  , DOI: ( /j.devcel ) Copyright © 2006 Elsevier Inc. Terms and Conditions

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