1. Effect of anaesthesia and cardiopulmonary bypass on blood endocannabinoid concentrations during cardiac surgery 
F Weis, A Beiras-Fernandez, D Hauer, C Hornuss, R Sodian, S Kreth, J Briegel, G Schelling 
British Journal of Anaesthesia 
Volume 105, Issue 2, Pages (August 2010)
DOI: /bja/aeq117
Copyright © 2010 The Author(s) Terms and Conditions

2. Fig 1
Changes in plasma concentrations of the endocannabinoids AEA and 2-AG before, during and after CS. Data presented as mean (sem). Preop, measurements in the awake patient before induction of anaesthesia; Anaesthesia, after induction of anaesthesia but before surgery; Surgery, measurements during surgery (sternotomy); Intra-CPB, during CPB; Post-CPB, after termination of CPB; ICU, values at admission to the cardiovascular ICU. *Significantly higher AEA plasma concentrations in the awake patient before induction of anaesthesia when compared with all other time points (unadjusted P<0.001, critical level=0.010, one-way rm-anova with the Holm–Sidak post hoc test). #Significantly higher 2-AG plasma concentrations during surgery and CPB compared with baseline values in the awake state (unadjusted P≤0.002, critical level ≤0.013).
British Journal of Anaesthesia  , DOI: ( /bja/aeq117)
Copyright © 2010 The Author(s) Terms and Conditions

3. Fig 2
Correlation between preoperative plasma anandamide concentrations and patients’ BMI. Preoperative plasma AEA concentrations correlated positively with the patients’ preoperative BMI (r=0.43; P=0.02).
British Journal of Anaesthesia  , DOI: ( /bja/aeq117)
Copyright © 2010 The Author(s) Terms and Conditions