1. Isotonix® Bromelain Plus

2. FDA Disclaimer
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease

3. What Do Enzymes Do?
Enzymes get overlooked for the powerhouses they are:
Help the body function properly.
Trigger the production of hormones & muscles
Support healthy metabolism
Without enzymes:
Food cannot be broken down for energy
Metabolism becomes sluggish, or stops all together
Cellular health is arrested

4. Proteo = Protein Lytic = to separate or dissolve
Proteolytic Enzymes
Proteo = Protein Lytic = to separate or dissolve
Proteolytic enzymes modulate:
Blood proteins (fibrin)
Antioxidant levels
Kinnins-Cytokine and Chemokine
levels
Cellular adhesion molecules
Reactive oxygen species
A failure to balance any of the above may lead to less than optimal immunity, cell division or repair of internal mechanisms.

5. One such enzyme: Bromelain
Derived from pineapple fruit and stems
Used for centuries in Central and South America to support digestion and inflammation
In modern times, used in muscle support formulas, post-injury support and in various other formulas.

6. Bromelain for Health
Bromelain seems to cause the body to produce substances that fight pain and swelling (inflammation).
Bromelain also contains chemicals that interfere with the growth of tumor cells and slow blood clotting.
Possibly as effective as prescription painkillers for arthritis (osteoarthritis) pain and knee function*
*when used in combination with additional proteases.
Source: WebMD.com

7. Bromelain and Cell Health
Bromelain can make it easier for your immune system to detect unhealthy cells and offer superior cellular protection.
Abnormal cellular activity – unhealthy cells – can go undetected in the body

8. Bromelain and Cell Health
Inside our bodies, many unhealthy cells “disguise” themselves from the immune system using a protective protein shield
Protective
Protein Layer
Unhealthy
Cell
Proteolytic Enzymes like bromelain can blast this protective layer, promoting the removal of cellular debris and allowing the immune system to do its job.
Bromelain introduced
Protein Layer
breaks down

9. Protease: A Special Kind of Enzyme
As systemic enzymes, proteases have shown effects on inflammation and recovery
Studies indicate that oral proteases work on inflammation mediators
Work to decrease issues associated with trauma

10. Bromelain: Proteolytic Enzyme & Protease
May enhance recovery from injuries and surgeries.
Breaking down fibrins that often lead to blood clots
Assists the breakdown of proteins formed during inflammation
Breaking fibrins may also help eliminate tissue swelling
Helpful when proteins bind abnormally and need to be dissolved or broken down
Improves other immune mechanisms by promoting efficiency of immune cells (T-cells)
Another role bromelain plays with its tough proteolytic enzymes is busting up clots beginning to form among blood platelets. This is good news for anyone dealing with cardiovascular problems.
Everyone may benefit from Bromelain. Due to its health-boosting properties and anti-inflammatory abilities, it is commonly administered to patients after surgery. It can help reduce pain and swelling in the body especially post-surgery

11. Bromelain & Inflammation
Inflammation is a process in which the body's white blood cells and chemicals help protect us from infection and foreign substances such as bacteria and viruses.
In some instances, the immune system triggers an inflammatory response when there are no foreign substances to fight off.
The body's normally protective immune system causes damage to its own tissues, and the body responds as if normal tissues are infected or somehow abnormal.

12. Bromelain & Inflammation
Arthritis is a general term that describes inflammation in joints. Some types of arthritis associated with inflammation include:
Rheumatoid arthritis
Psoriatic arthritis
Gouty arthritis
Systemic lupus erythematosus

13. Bromelain & Inflammation
Inflammation can affect organs as part of an autoimmune disorder. For example:
Inflammation of the heart (myocarditis) may cause vague chest pain.
Inflammation of the kidneys (nephritis) may cause high blood pressure.
Inflammation of the blood vessels (vasculitis) may cause rash, headaches, or internal organ damage.

14. Bromelain & Inflammation
“Bromelain can be used to treat a number of conditions, but it is particularly effective in reducing inflammation from infection and injuries.”
“It is often used to reduce inflammation from tendinitis, sprains and strains, and other minor muscle injuries. Studies of people having dental, nasal, and foot surgeries found it did reduce inflammation.”
Source: Bromelain | University of Maryland Medical Center

15. What is White Willow Bark?
White willow bark is a tree native to Europe and Asia. The name "white willow" comes from the color of the leaves, which are covered with fine white hairs.
Historically, white willow bark has been used by ancient Egyptians for inflammation, and the Greeks to relieve pain and fever.

16. Research on White Willow Bark
Willow Bark constituents include Flavonoids, Tannins and Salicylates.
The active constituent of willow bark is thought to be salicin, which is metabolized to salicylic acid in the body.
Salicylic acid is known for its ability to ease aches and pains.
Its effects as an anti-inflammatory agent are due to its work on various inflammatory mediators in the body such as the prostaglandins.

17. Research on White Willow Bark
Effects as an anti-inflammatory agent are due to its work on various inflammatory mediators in the body.
In clinical studies, white willow bark has demonstrated effects on pain.
Anti-inflammatory agent
Shown to support normal blood platelet aggregation and promote healthy blood flow
Its effects as an anti-inflammatory agent are due to its work on various inflammatory mediators in the body such as the prostaglandins.

18. Three Powerful Ingredients
Bromelain
Isotonix® Bromelain Plus
Proteases
White Willow Bark

19. Isotonix® Bromelain Plus
Isotonix Bromelain Plus supports your body’s natural inflammatory response, promoting natural tissue recovery
Resulting from:
Mechanical stress to connective tissues
Natural buildup of pro-oxidants from physical activity
Environmental or internal stressors to sinus, nasal, lung and respiratory function
Although studies show mixed results, bromelain may reduce swelling, bruising, healing time, and pain after surgery and physical injuries. It is often used to reduce inflammation from with tendinitis, sprains and strains, and other minor muscle injuries. Studies of people having dental, nasal, and foot surgeries found it did reduce inflammation. In Europe, bromelain is used to treat sinus and nasal swelling following ear, nose, and throat surgery or trauma.

20. Isotonix® Bromelain Plus
Isotonix Bromelain Plus works synergistically with the body’s own repair system
Helps to remove extra cellular proteins damaged by free radicals.
Promoting the body’s natural healing process.
Isotonix Bromelain Plus provides ingredients with beneficial activity to support tissue health.
Although studies show mixed results, bromelain may reduce swelling, bruising, healing time, and pain after surgery and physical injuries. It is often used to reduce inflammation from with tendinitis, sprains and strains, and other minor muscle injuries. Studies of people having dental, nasal, and foot surgeries found it did reduce inflammation. In Europe, bromelain is used to treat sinus and nasal swelling following ear, nose, and throat surgery or trauma.

21. Isotonix® Bromelain Plus
Protect · Repair · Heal
Your body needs protection,
whether from unhealthy cells on the inside
or everyday wear and tear on the outside.
Thanks to its unique formula,
Isotonix® Bromelain Plus
helps protect your body from both.