1. RELEASE OF SOME GROWTH FACTORS FROM CGF-TCP
A part of the results of this study referred to the relase of growth factors from CGF alone are enclosed in a submitted paper (Borsani et al. 2015)

2. Comments:
IGF-1 and BMP-2 showed different release .
In particular with round-up and TCP:
-The release of IGF-1 is lower at all time points.
-The release of BMP-2 increases (very much) at all time point.

3. BMP-2 in vitro release 5hours 1day 3days 6days 8days
% CGF without round up
% CGF round up
% CGF + TCP round up
5hours 2,
1239,0625
1438,125
1day
30,
1310,494792
1692,708333
3days
43,535
1650,729167
1849,791667
6days
33,
1401,96875
1776,666667
8days
82,
1118,541667
1768,541667

4. BMP-2 in vitro release
% of release
Experimental times

5. IGF-1 in vitro release % media CGF without round up
% media CGF without round up
% media CGF round up
% media CGF + TCP round up
5hours
97,
48,
120,
1day
91,
44,
80,
3days
98,
45,
85,
6days
132,53937
59,
80,
8days
129,
59,
91,

6. IGF-1 in vitro release
% of release
Experimental times