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Dectin-1 is repressed in allergic individuals.
Dectin-1 is repressed in allergic individuals. CLEC7A expression in (A) bronchial epithelial cells (BEC) from controls and asthmatics and (B) NECs from control and CRS patients. (C) IL-33 levels in control and CRS NECs stimulated with media or HDM for 2 hours. (A to C) Data are means + SEM from n = 6 to 19 patients per group (A and B) or from a minimum of 7 patients (C). *P < 0.05, as determined by Student’s t test with Welch’s correction or one-way ANOVA followed by post hoc (Newman-Keuls) analysis. Naina Gour et al. Sci. Immunol. 2018;3:eaam9841 Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works
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