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Total and differential cell counting in the broncho-alveolar lavage of mice exposed to CS or air during 3 or 6 months. Total and differential cell counting in the broncho-alveolar lavage of mice exposed to CS or air during 3 or 6 months. Total (A) and differential (B–D) cell counting. Notice that the data at 3 and 6 months refer to data of separate groups of animals. Total cell counts increased with CS exposure and this effect was already present after 3 months of exposure (A). This was associated with a shift towards an abundant number of neutrophils (B), lymphocytes (C) and macrophages (D). Each square represents data of an individual mouse; horizontal line represents mean and vertical lines the standard deviation. **P<0.01; ***P<0.001. Manuela Rinaldi et al. Dis. Model. Mech. 2012;5: © Published by The Company of Biologists Ltd
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