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Figure 1. Concentrations of CSF markers in gene-expansion negative controls and premanifest and manifest gene-expansion carriers Concentrations of CSF.

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Presentation on theme: "Figure 1. Concentrations of CSF markers in gene-expansion negative controls and premanifest and manifest gene-expansion carriers Concentrations of CSF."— Presentation transcript:

1 Figure 1. Concentrations of CSF markers in gene-expansion negative controls and premanifest and manifest gene-expansion carriers Concentrations of CSF markers in gene-expansion negative controls and premanifest and manifest gene-expansion carriers Age- and sex-adjusted concentrations of CSF markers in gene-expansion negative controls (GEN C), premanifest gene-expansion carriers (P GEC), and manifest gene-expansion carriers (M GEC). Markers were adjusted to the level of a 45-year-old man. Markers of neurodegeneration: (A) neurofilament light polypeptide (NFL); (B) myelin basic protein (MBP); (C) microtubule-associated protein tau (Tau). Markers of neuroinflammation: (D) osteopontin (OPN); (E) chitinase-3-like 1 (CHI3L1): (F) terminal complement complex (TCC). Markers of oxidative stress: (G) total nitric oxide (NOx). The p values were obtained from linear regression analysis and Bonferroni correction. Tua Vinther-Jensen et al. Neurol Neuroimmunol Neuroinflamm 2016;3:e287 © 2016 American Academy of Neurology

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