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Serlopitant reduced pruritus in patients with prurigo nodularis in a phase 2, randomized, placebo-controlled trial  Sonja Ständer, MD, Paul Kwon, MD,

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Presentation on theme: "Serlopitant reduced pruritus in patients with prurigo nodularis in a phase 2, randomized, placebo-controlled trial  Sonja Ständer, MD, Paul Kwon, MD,"— Presentation transcript:

1 Serlopitant reduced pruritus in patients with prurigo nodularis in a phase 2, randomized, placebo-controlled trial  Sonja Ständer, MD, Paul Kwon, MD, Joe Hirman, PhD, Andrew J. Perlman, MD, PhD, Elke Weisshaar, MD, Martin Metz, MD, Thomas A. Luger, MD  Journal of the American Academy of Dermatology  Volume 80, Issue 5, Pages (May 2019) DOI: /j.jaad Copyright © 2019 American Academy of Dermatology, Inc. Terms and Conditions

2 Fig 1 Changes from baseline over time. A, Percentage change from baseline in mean average itch visual analog scale (VAS) score at weeks 2, 4, and 8. Asterisks indicate P < .05 for the mean difference of serlopitant versus placebo. B, Forest plot of average intensity with standard error (SE) for average itch VAS score change from baseline at weeks 4 and 8, by subgroup (intention-to-treat population). Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2019 American Academy of Dermatology, Inc. Terms and Conditions

3 Fig 2 Changes from baseline over time. Percentage change from baseline in least squares mean average itch numeric rating scale (NRS) score at weeks 2, 4, and 8. Asterisk indicates P ≤ .05 for the mean difference of serlopitant versus placebo. SE, Standard error. Journal of the American Academy of Dermatology  , DOI: ( /j.jaad ) Copyright © 2019 American Academy of Dermatology, Inc. Terms and Conditions


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