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Small-caliber heparin-coated ePTFE grafts reduce platelet deposition and neointimal hyperplasia in a baboon model  Peter H Lin, MD, Changyi Chen, MD,

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Presentation on theme: "Small-caliber heparin-coated ePTFE grafts reduce platelet deposition and neointimal hyperplasia in a baboon model  Peter H Lin, MD, Changyi Chen, MD,"— Presentation transcript:

1 Small-caliber heparin-coated ePTFE grafts reduce platelet deposition and neointimal hyperplasia in a baboon model  Peter H Lin, MD, Changyi Chen, MD, PhD, Ruth L Bush, MD, Qizhi Yao, MD, PhD, Alan B Lumsden, MD, Stephen R Hanson, PhD  Journal of Vascular Surgery  Volume 39, Issue 6, Pages (June 2004) DOI: /j.jvs

2 Fig 1 Diagram of small-caliber expandable polytetrafluoroethylene (ePTFE) bilateral aortoiliac bypass grafting with end-to-side anastomoses. Intervening segments of the distal aorta and proximal common iliac arteries were ligated. Heparin-coated ePTFE graft was placed on one side, and non-coated ePTFE graft was placed contralaterally and served as a paired internal control. Journal of Vascular Surgery  , DOI: ( /j.jvs )

3 Fig 2 Neointimal hyperplasia at proximal anastomoses. Collagens are blue; elastin is black; others are red. A, Proximal anastomosis of untreated expandable polytetrafluoroethylene (ePTFE) graft (control). B, Proximal anastomosis of heparin-coated ePTFE graft (treated). L, Lumen; N, neointima; G, ePTFE graft material. (Verhoeff-Masson stain; original magnification ×40). Journal of Vascular Surgery  , DOI: ( /j.jvs )

4 Fig 3 Neointimal hyperplasia at distal anastomoses. Collagens are blue; elastin is black; others are red. A, Distal anastomosis of untreated expandable polytetrafluoroethylene (ePTFE) graft (control). B, Distal anastomosis of heparin-coated ePTFE graft (treated). L, Lumen; N, neointima; G, ePTFE graft material. (Verhoeff-Masson stain; original magnification ×40) Journal of Vascular Surgery  , DOI: ( /j.jvs )

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