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In situ analysis of Dp1-deficient conceptuses at E6.5.
In situ analysis of Dp1-deficient conceptuses at E6.5. Decidua containing a wild-type (A,D,G) and two abnormal, presumptive Dp1 mutants (B,C,E,F,H,I) conceptuses were analyzed after serial sectioning. (A-C) Hematoxylin and Eosin staining. (D-F) Immunohistochemical staining with TROMA1 to detect trophectoderm-derived tissue. (G-I) BrdU incorporation after a 2 hour in vivo labeling. The star indicates the position of the ectoplacental cone (EPC) and secondary trophoblastic giant (TG) cells at the proximal pole of the conceptus. The arrowheads indicate the positions of a trophoblast giant cell. Matthew J. Kohn et al. Development 2003;130: © 2003.
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