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Altered oligodendrocyte progenitor cell (OPC) marker protein expression in two white matter regions of ShhΔFP/ΔFP and SmoΔNT/ΔNT embryos at E15.5. Altered.

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Presentation on theme: "Altered oligodendrocyte progenitor cell (OPC) marker protein expression in two white matter regions of ShhΔFP/ΔFP and SmoΔNT/ΔNT embryos at E15.5. Altered."— Presentation transcript:

1 Altered oligodendrocyte progenitor cell (OPC) marker protein expression in two white matter regions of ShhΔFP/ΔFP and SmoΔNT/ΔNT embryos at E15.5. Altered oligodendrocyte progenitor cell (OPC) marker protein expression in two white matter regions of ShhΔFP/ΔFP and SmoΔNT/ΔNT embryos at E15.5. (A-P) Olig2 and Pdgfrα (A-H) and Nkx2.2 and Sox10 (I-P) expression in the dorsal funiculus (DF) and ventral funiculus (VF) in WT, ShhΔFP/ΔFP, ShhΔFP/ΔFP;Gli3xt/xt and SmoΔNT/ΔNT embryos. Dotted white lines indicate the boundaries of the white matter. (Q,R) Cell counts for each marker for the indicated genotypes (key above A-D). (S) Schematic indicating the area of the spinal cord shown in the panels above. *P<0.05; Student’s two-tailed t-test. Error bars indicate s.e.m. Scale bar: 100 μm. Kwanha Yu et al. Development 2013;140: © Published by The Company of Biologists Ltd

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