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Serum Protein Profiles in Myasthenia Gravis

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Presentation on theme: "Serum Protein Profiles in Myasthenia Gravis"— Presentation transcript:

1 Serum Protein Profiles in Myasthenia Gravis
Chao Cheng, MD, PhD, Guoyong Wu, MD, Sai-Ching J. Yeung, MD, PhD, Rong Li, MD, PhD, Amos Ela Bella, MS, Jinzhuo Pang, MD, Fo-tian Zhong, MD, Honghe Luo, MD, Yanli Jin, MS, Jingxuan Pan, MD, PhD  The Annals of Thoracic Surgery  Volume 88, Issue 4, Pages (October 2009) DOI: /j.athoracsur Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Representative surface-enhanced laser desorption/ionization spectra comparison of serum between the myasthenia gravis (MG) patients and healthy control groups. In the MG sera, the proteins at M , M , M , and M were decreased in comparison with the normal control sera. The x axis shows the molecular weight for each spectrum (mass/charge ratio values), and the y axis shows the relative intensity. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 In the training data set, the Biomarker Pattern Software built the classification tree to classify myasthenia gravis patients or healthy controls. All the sera were categorized for a sensitivity and specificity of 100% and 89.3%, respectively, using peak at M Da, M Da as splitters. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2009 The Society of Thoracic Surgeons Terms and Conditions


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