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Covering the Cover Gastroenterology

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Presentation on theme: "Covering the Cover Gastroenterology"— Presentation transcript:

1 Covering the Cover Gastroenterology
Anson W. Lowe, Richard H. Moseley  Gastroenterology  Volume 144, Issue 4, Pages (April 2013) DOI: /j.gastro Copyright © Terms and Conditions

2 Figure 1 Type II achalasia has a higher success rate compared with type I achalasia (P < .01) and type III achalasia (P < .001), as shown in a Kaplan–Meier curve. Gastroenterology  , DOI: ( /j.gastro ) Copyright © Terms and Conditions

3 Figure 2 An 18-mm sigmoid polyp seen with (A) MR with contrast enhancement, (B) MR without contrast, and (C) colonoscopy. Gastroenterology  , DOI: ( /j.gastro ) Copyright © Terms and Conditions

4 Figure 3 Summary of characteristics of ICC classes. Specific molecular and clinical characteristics differ between ICC classes. Molecular characteristics such as signatures of poor prognosis (ie, cluster A, CC-like, G3, S1, S2, and stem-cell like ICC), oncogenic pathways (ie, IGF1R, MET, EGFR), gene expression (ie, EGFR, ILs), copy number variations, and oncogenes mutations (KRAS and EGFR) are differentially enriched in the proliferation and inflammation classes. Clinical characteristics such as moderate/poorly differentiated tumors and intraneural invasion are more frequent in the proliferation class. Differences in survival and recurrence were observed. Gastroenterology  , DOI: ( /j.gastro ) Copyright © Terms and Conditions


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