1. Alpha to Beta Cell Reprogramming: Stepping toward a New Treatment for Diabetes 
Anna B. Osipovich, Mark A. Magnuson 
Cell Stem Cell 
Volume 22, Issue 1, Pages (January 2018)
DOI: /j.stem
Copyright © 2017 Elsevier Inc. Terms and Conditions

2. Figure 1
Reversal of Diabetes by the Endogenous Reprogramming of Alpha Cells into Beta Cells
Infusion of AAV expressing Pdx1 and Mafa directly into the pancreatic duct of diabetic mice reprograms alpha cells into beta cells, restoring normal insulin secretion for up to 4 months. Similar results were obtained using toxin-treated human islets.
Cell Stem Cell  , 12-13DOI: ( /j.stem )
Copyright © 2017 Elsevier Inc. Terms and Conditions