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OCT and IOP analysis of 2-3-month-old AP-2β NCC KO mutants.

Published byΙσίδωρος Παπαϊωάννου Modified over 5 years ago

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Presentation on theme: "OCT and IOP analysis of 2-3-month-old AP-2β NCC KO mutants."— Presentation transcript:

1 OCT and IOP analysis of 2-3-month-old AP-2β NCC KO mutants.
OCT and IOP analysis of 2-3-month-old AP-2β NCC KO mutants. OCT images of the anterior chamber of a control littermate (A) and an AP-2β NCC KO mutant (B) at 2 to 3 months of age. White arrows in A and B show relative positions of the cornea and iris, with adherence of the iris to the cornea in B. The presence of round foramina in the corneal stroma of the mutant is shown by red arrowheads (B). (C) A comparison of IOP between 3-month-old AP-2β NCC KO mutants and their control littermates. Individual measurements are overlaid on bar graph comparing IOP between control mice and AP-2β NCC KO mutant mice. Mutant mice have increased IOP (28.87 mmHg±5.19, n=12) relative to their control littermates (9.76 mmHg±1.88, n=12). Measurements taken with a Rebound Tonometer (TonoLab Vantaa, Finland). Results are mean±s.d. *P< (Student's two-tailed t-test). Vanessa B. Martino et al. Dis. Model. Mech. 2016;9: © Published by The Company of Biologists Ltd

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