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Comparative total and unbound pharmacokinetics of cefazolin administered by bolus versus continuous infusion in patients undergoing major surgery: a randomized.

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Presentation on theme: "Comparative total and unbound pharmacokinetics of cefazolin administered by bolus versus continuous infusion in patients undergoing major surgery: a randomized."— Presentation transcript:

1 Comparative total and unbound pharmacokinetics of cefazolin administered by bolus versus continuous infusion in patients undergoing major surgery: a randomized controlled trial  B.I. Naik, C Roger, K Ikeda, M.S. Todorovic, S.C. Wallis, J Lipman, J.A. Roberts  British Journal of Anaesthesia  Volume 118, Issue 6, Pages (June 2017) DOI: /bja/aex026 Copyright © 2017 The Author(s) Terms and Conditions

2 Fig 1 The observed mean (sd) total and unbound cefazolin concentration–time profiles for intermittent (black lines) and continuous infusions (grey lines) for n=20 patients. II: Intermittent Infusion, CI: Continuous Infusion, CONC: Concentration, UNB: Unbound British Journal of Anaesthesia  , DOI: ( /bja/aex026) Copyright © 2017 The Author(s) Terms and Conditions


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