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Diabetic FXR KO kidney showed increased lipid accumulation.

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1 Diabetic FXR KO kidney showed increased lipid accumulation.
Diabetic FXR KO kidney showed increased lipid accumulation. A: Oil red O staining of kidney sections and kidney lipid content showing lipid accumulation in diabetic FXR KO kidneys. G, glomerulus. B: Analysis of renal mRNA expression by quantitative real-time PCR for SREBP-1c, FAS, ACC, SCD-1, LDLR, and LOX-1 in isolated glomeruli. *P < 0.05 vs. diabetic wild-type C57BL/6J mice on WD or as specified (n = 6 mice per group). (A high-quality digital representation of this figure is available in the online issue.)‏ Xiaoxin X. Wang et al. Diabetes 2010;59: ©2010 by American Diabetes Association

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