1. IQGAPs localize at the tips of axons in hippocampal neurons.
IQGAPs localize at the tips of axons in hippocampal neurons. (A) Localization of the IQGAP family in stage 3 hippocampal neurons. The cells were labeled with each anti-IQGAP antibody (red), anti-unique β-tubulin (TUJ1) antibody (green), and Alexa Flour 647-phalloidin (blue). The regions in white boxes are shown magnified (right). The results shown are representative of five independent experiments. Bar, 20 μm. (B) Detailed localization of the IQGAP family in the growth cones. The cells on PDL alone were labeled as described in A. The results shown are representative of six independent experiments. Bar, 5 μm.
Shujie Wang et al. J Cell Sci 2007;120:
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