1. Left: Alternations in cardiac output (black) in one typical patient, every 60 s for three cycles, are followed by oscillations in end-tidal CO2 (blue) and ventilation (red), when no dynamic CO2 is applied.
Left: Alternations in cardiac output (black) in one typical patient, every 60 s for three cycles, are followed by oscillations in end-tidal CO2 (blue) and ventilation (red), when no dynamic CO2 is applied. Right: Oscillations in end-tidal CO2 (blue) and ventilation (red), in the same patient, are attenuated when dynamic CO2 is delivered where the troughs in end-tidal CO2 are predicted (around peak ventilation). The motor valve position profile (green), which is proportional to the dose of CO2 delivered, varies in size and shape dependent on the amplitude and phase of the current ventilatory signal in real time. While ventilation is still oscillatory, the amplitude of the oscillations are diminished.
Resham Baruah et al. Open Heart 2014;1:e000055
©2014 by British Cardiovascular Society