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Folic Acid: Cellular Uptake and Penetration into Human Skin

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1 Folic Acid: Cellular Uptake and Penetration into Human Skin
Anja Knott, Heiko Mielke, Urte Koop, Rainer Wolber, Thorsten Burkhardt, Jens-Peter Vietzke, Franz Stäb, Horst Wenck, Stefan Gallinat  Journal of Investigative Dermatology  Volume 127, Issue 10, Pages (October 2007) DOI: /sj.jid Copyright © 2007 The Society for Investigative Dermatology, Inc Terms and Conditions

2 Figure 1 Folic acid uptake by cultured HDFs and RFC-1 mRNA regulation after UV exposure. (a) Dose-dependent uptake of folic acid by cultured HDFs. (b) UV-dependent uptake of folic acid by cultured HDFs. (c) UV irradiation increases RFC-1 mRNA expression in dermis and epidermis. Journal of Investigative Dermatology  , DOI: ( /sj.jid ) Copyright © 2007 The Society for Investigative Dermatology, Inc Terms and Conditions

3 Figure 2 Folic acid penetrates human skin in vivo.
Journal of Investigative Dermatology  , DOI: ( /sj.jid ) Copyright © 2007 The Society for Investigative Dermatology, Inc Terms and Conditions


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