1. 2.3 Mitosis

2. Warm-up Essential Question What is DNA? What is it’s role in the body?
Why do cells divide and what are the steps to division?

3. New vocabulary
chromosomes – made up of DNA tightly coiled into a manageable package
chromatids – replicated chromosomes- “sister” chromatids that are copies
centromeres – where sister chromatids are connected

5. Why do cells grow? Do they have to divide?
Cells are limited in size because the outside (the cell membrane) must transport the food and oxygen to the parts inside
As a cell gets bigger, the outside is unable to keep up with the inside, because the inside grows a faster rate than the outside
It’s about surface area to volume!
When they get to big to support the inside, they divide into two cells

6. The Cell Cycle
The stages in which a cell goes through in order to divide
Divided into 4 phases:
G1( normal growth),
S ( replicate DNA),
G2 ( protein synthesis),
M ( mitosis) /Cytokinesis

7. Interphase G1, S, and G2 The “in-between phase”
Cell is growing and developing
Copies DNA
Prepares for division (mitosis)
Makes Centrioles (used in Mitosis)

8. Mitosis
part of eukaryotic cell division during which the cell nucleus divides
divided into 4 parts
Prophase
Metaphase
Anaphase
Telophase

9. Prophase “preparation” phase – getting ready to divide
chromatin condenses into chromosomes
centrioles separate, spindles begin to form
nuclear membrane breaks down

10. Metaphase “middle phase” chromosomes line up in the middle of the cell
spindle fibers connect chromatids to centromere
no nuclear membrane

11. Anaphase “apart phase”
The spindles pull the sister chromatids apart towards opposite sides

12. Telophase chromosomes gather at opposite ends
chromosomes lose distinct shape (unravels)
Two new nuclear envelope reforms

13. Cytokinesis division of cytoplasm into two new daughter cells
cytoplasm pinches in half
each new cell has identical set of duplicate chromosomes

14. I(PMAT)C I Picked My Apples Today Carefully
I Passed My Anatomy Test Calmly
I Prefer Milk And Tea, Carrie

15. Warm-up
Write 3 level 1, 2 level 2 and 1 level 3 questions about the cell cycle.

17. Write a summary of the cell cycle
Your summary should answer the essential question!