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The effects of prostanoids on vasculature and blood cells; a variety of vascular cells, platelets and leukocytes have been identified as targets for the.

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Presentation on theme: "The effects of prostanoids on vasculature and blood cells; a variety of vascular cells, platelets and leukocytes have been identified as targets for the."— Presentation transcript:

1 The effects of prostanoids on vasculature and blood cells; a variety of vascular cells, platelets and leukocytes have been identified as targets for the antiproliferative, anti-inflammatory and anti-aggregatory actions of prostaglandins. The effects of prostanoids on vasculature and blood cells; a variety of vascular cells, platelets and leukocytes have been identified as targets for the antiproliferative, anti-inflammatory and anti-aggregatory actions of prostaglandins. SMC: smooth muscle cells; EC: endothelial cells; Mono: mononuclear cells; NF: nuclear factor; TNF: transforming nuclear factor; IL: interleukin; MA: macrophages; MAPK: mitogen-activated protein kinase; iNOS: inducible nitric oxide synthase; PMN: polymorphonuclear neutrophils; Burst: generation of reactive oxygen species. Reproduced from [38] with permission from the publisher. Olivier Sitbon, and Anton Vonk Noordegraaf Eur Respir Rev 2017;26:160055 ©2017 by European Respiratory Society

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