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Compliments of Factor H: What’s in it for AMD?

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Presentation on theme: "Compliments of Factor H: What’s in it for AMD?"— Presentation transcript:

1 Compliments of Factor H: What’s in it for AMD?
Mary J. Mattapallil, Rachel R. Caspi  Immunity  Volume 46, Issue 2, Pages (February 2017) DOI: /j.immuni Copyright © Terms and Conditions

2 Figure 1 CFH-CD11b Complex Binds to CD47 on Microglial Cells in the Retina, Competing with Binding of TSP1 The consequence of this interaction is inhibition of CD47 driven clearance of mononuclear phagocytes, whose role is removal of physiological waste products, promoting inflammation characteristic of AMD. Immunity  , DOI: ( /j.immuni ) Copyright © Terms and Conditions


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