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Published byGerda Veenstra Modified over 5 years ago
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The microbiota downregulate CD160 expression on IELs
The microbiota downregulate CD160 expression on IELs. (A) CD160 expression levels on TCRβ+ and TCRγδ+ colonic IELs from mice given regular drinking water (H2O, blue) and mice treated with mixture of antibiotics for 4 wk mice (ABX, red). The microbiota downregulate CD160 expression on IELs. (A) CD160 expression levels on TCRβ+ and TCRγδ+ colonic IELs from mice given regular drinking water (H2O, blue) and mice treated with mixture of antibiotics for 4 wk mice (ABX, red). Representative plots are shown to the left and summary of CD160 mean fluorescence intensity (MFI) to the right. (B) CD160 expression levels on TCRβ+ and TCRγδ+ colonic IELs from age- and sex-matched SPF mice (blue) and GF mice (red). Representative plots are shown to the left and summary of CD160 MFI to the right. The results are representative of at least three independent experiments. Significance was assessed using Student t test. *p < 0.05, **p < 0.01, ***p < 0.005, ****p < Catherine L. Tan et al. ImmunoHorizons 2018;2: Copyright © 2018 The Authors
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