1. Unchanged worm burden and microfilaremia in basophil-deficient mice compared with their basophil-competent littermates.
Unchanged worm burden and microfilaremia in basophil-deficient mice compared with their basophil-competent littermates. Basophil-deficient Mcpt8-cre and their competent littermates (Mcpt8-wt) were infected with L. sigmodontis. (A) Numbers of worms were counted at the indicated time points in basophil-deficient and -competent mice. Each dot represents the worm burden from a single mouse (n = 9–11 mice). Data were analyzed with an unpaired Student t test. MF were counted in 20 μl blood of basophil-deficient Mcpt8-cre and basophil-competent Mcpt8-wt mice (B) at the indicated days p.i. Data show the mean plus SEM and are combined from two independent experiments (n = 11–12 mice). Microfilaremia was analyzed with a two-way ANOVA with Bonferroni posttest.
Wiebke Hartmann et al. ImmunoHorizons 2018;2:
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