1. Efficacy and Safety of Transdermal Buprenorphine: A Randomized, Placebo-Controlled Trial in 289 Patients with Severe Cancer Pain 
Philippe Poulain, MD, Willy Denier, MD, Joep Douma, MD, Klaus Hoerauf, MD, PhD, Mirko Šamija, MD, Maciej Sopata, MD, Gernot Wolfram, MD 
Journal of Pain and Symptom Management 
Volume 36, Issue 2, Pages (August 2008)
DOI: /j.jpainsymman
Copyright © 2008 U.S. Cancer Pain Relief Committee Terms and Conditions

2. Fig. 1
Patient flow chart. aMultiple reasons for discontinuation of study could be mentioned.
Journal of Pain and Symptom Management  , DOI: ( /j.jpainsymman )
Copyright © 2008 U.S. Cancer Pain Relief Committee Terms and Conditions

3. Fig. 2
Mean daily pain intensity (a) and mean intake of rescue medication (b) during the run-in phase and maintenance phase. NRS pain scores and consumption of rescue medication are given as mean+95% confidence intervals.
Journal of Pain and Symptom Management  , DOI: ( /j.jpainsymman )
Copyright © 2008 U.S. Cancer Pain Relief Committee Terms and Conditions