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2 http://www. goldiesroom. org/video_archive. htm https://duckduckgo

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7 Molecule Compound Atom

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9 Elements of Life 96% of living organisms is made of: carbon (C)
hydrogen (H) oxygen (O) nitrogen (N)

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11 Are complex (big) Are simple (small)

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14 Molecules of Life Put elements C, H, O, N together in different ways to build living organisms What are bodies made of? 4 ORGANIC MOLECULES carbohydrates sugars & starches proteins fats (lipids) nucleic acids DNA, RNA

15 Repair and maintenance
FOOD? Which type of molecules make food? Think of a pizza slice… Carbohydrates? Protein? Fats/Lipids Nucleic acids (DNA and RNA) Why do we have to eat? Energy Growth Repair and maintenance

16 How do you use food? Carbohydrates? (bread) For energy
Protein? (Cheese) Building block of cells/body Fats/Lipid? (cheese) As stored energy YES !

17 ATP Why do we eat? We eat to take in more of these chemicals
Food for building materials to make more of us (cells) for growth for repair Food to make energy to make ATP ATP

18 Who makes organic molecules
Hint: think of your favorite organic molecule Glucose Plants What do plants do with the extra sugar (leftover after they use sugar by __________ it to make __________) They store it as STARCH! How do they make starch?

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20 What are living creatures made of? Why do we have to eat?
The Chemistry of Life What are living creatures made of? Why do we have to eat? Energy Growth Repair and maintenance

21 Why do we need to eat? Foods to give you more building blocks & more energy for building & running bodies Which ones are food? carbohydrates proteins fats nucleic acids vitamins minerals, salts water

22 Don’t forget water Water Rest of you is made of carbon molecules
65% of your body is H2O water is inorganic doesn’t contain carbon Rest of you is made of carbon molecules organic molecules carbohydrates proteins fats nucleic acids

23 What do we use the organic molecules for?
Carbohydrates Source of energy Proteins Building blocks of the body Lipids Source of stored energy

24 OH H HO CH2OH O Carbohydrates: Energy molecules

25 Carbohydrates

26 Carbohydrates Function: Examples quick energy energy storage structure
cell wall in plants Examples sugars starches cellulose (cell wall) Glycogen glucose C6H12O6 sucrose starch

27 A. CARBOHYDRATES Living things use carbohydrates as a key source of ENERGY! Plants use carbohydrates for structure (CELLULOSE) include sugars and complex carbohydrates (starches) Contain the elements carbon, hydrogen, and oxygen The hydrogen is in a 2:1 ratio to oxygen…always Ex C6H12O6

28 Simple sugars

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32 How do plants store extra glucose?
Starch How do animals store sugar/glucose? Glycogen

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34 + + H2O

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37 Dehydration Synthesis

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39 Building large organic molecules
Small molecules = building blocks Bond them together = polymers A Polymer is made up of repeating subunits

40 Building important polymers
Carbohydrates = built from sugars sugar – sugar – sugar – sugar – sugar – sugar Proteins = built from amino acids amino acid Nucleic acids (DNA) = built from nucleotides nucleotide – nucleotide – nucleotide – nucleotide A Polymer is made up of repeating subunits

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42 1. Monosaccharides (simple sugars)
all have the formula C6 H12 O6 all have a single ring structure (glucose is an example) Sugars end in –ose Ex. Glucose, Fructose, Galactose, Ribose, Deoxyribose

43 2. Disaccharides (double sugars)
all have the formula C12 H22 O11 sucrose (table sugar) is an example

44 3. Polysaccharides Formed of three or more simple sugar units
Glycogen - animal starch stored in liver & muscles Cellulose - indigestible in humans - forms cell walls Starches - used as energy storage

45 How to build large molecules?
Synthesis building bigger molecules from smaller molecules building cells & bodies repair growth reproduction + ATP

46 Building large molecules of life
Chain together smaller molecules building block molecules = monomers Big molecules built from repeating units of little molecules Polymers

47 sugar - sugar - sugar - sugar - sugar
Carbohydrates Building block molecules = sugars sugar - sugar - sugar - sugar - sugar sugar

48 How do we make these molecules?
We build them!

49 How do we combine simple sugars to make bigger sugars?
By the process called Dehydration Synthesis Dehydration- lose of water Synthesis- To make…

50 4. Dehydration Synthesis
Combining simple molecules to form a more complex one with the removal of water ex. monosaccharide + monosaccharide ----> disaccharide + water (C6H12O6 + C6H12O6 ----> C12H22O11 + H2O Polysaccharides are formed from repeated dehydration synthesis One example is starch…made by plants

51 amino acids = building block
Example of synthesis amino acids protein Proteins are synthesized by bonding amino acids amino acids = building block protein = polymer

52 How to take large molecules apart
Digestion taking big molecules apart getting raw materials for synthesis & growth making energy (ATP) for synthesis, growth & everyday functions + ATP

53 Example of digestion starch glucose Starch is digested to glucose ATP

54 https://duckduckgo. com/
Activity (dehydration synthesis and hydrolysis)

55 What is the Mechanism of digestion?
Hydrolysis

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57 Addition of WATER to a compound to SPLIT it into smaller subunits
5. Hydrolysis Addition of WATER to a compound to SPLIT it into smaller subunits (also called chemical digestion) ex. disaccharide + H2O ---> monosaccharide + monosaccharide C12 H22 O11 + H2 O ---> C6 H12 O6 + C6 H12 O6

58 Proteins

59 Multipurpose molecules
Proteins: Multipurpose molecules

60 Proteins Examples muscle skin, hair, fingernails, claws pepsin insulin
collagen, keratin pepsin digestive enzyme in stomach insulin hormone that controls blood sugar levels pepsin collagen (skin)

61 Do Now: How are the following 2 reactions different? Explain.
1) C12 H22 O H2O ---> C6 H12 O6 + C6 H12 O6 2) C6 H12 O6 + C6 H12 O6 ---> C12 H22 O H2O Note-Use the terms Dehydration synthesis, hydrolysis in your answer. Write A (on top right corner of the card) if you think your answer is correct and B if you are not sure/don’t know the answer. Ans: 1st is digestion of a disaccharide sugar by the mechanism of hydrolysis –addition of water 2nd is the synthesis of a disaccharide from 2 monosaccharide by the mechanism of dehydration synthesis- loss of water

62 Proteins —N— H | —C— C—OH || O Building block = amino acids –
20 different amino acids There’s 20 of us… like 20 different letters in an alphabet! Can make lots of different words —N— H | —C— C—OH || O variable group

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64 Proteins are polymers of amino acids
Small molecules = Amino acids (building blocks) Bond them together = Protiens (polymers)

65 There are 20 types of amino acids
C2H5OH C2H5 CH3 Only R group is different between the 20 types of amino acids

66 C. PROTEINS contain the elements carbon, hydrogen, oxygen, and nitrogen composed of MANY amino acid subunits It is the arrangement of the amino acid that forms the primary structure of proteins. The basic amino acid form has a carboxyl group on one end, a methyl group that only has one hydrogen in the middle, and a amino group on the other end. Attached to the methyl group is an R group.

67 C. PROTEINS contain the elements carbon, ____________________________
composed of MANY amino acid subunits It is the arrangement of the __________that forms the primary structure of proteins. The basic amino acid form has a _________ group on one end, a __________ group that only has one hydrogen in the middle, and a ___________on the other end. Attached to the methyl group is an ___ group.

68 8. Dipeptide formed from two amino acid subunits
Formed by the process of Dehydration Synthesis amino acid + amino acid dipeptide + water

69 Synthesis of a dipeptide
Mechanism is called-Dehydration synthesis Amino acid + amino acid ---> dipeptide + H2O (Chemical reaction in words) (Chemical reaction in formula)

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72 amino acids = building block
Example of synthesis amino acids protein Proteins are synthesized by bonding amino acids amino acids = building block protein = polymer

73 9. Hydrolysis of a dipeptide
Breaking down of a dipeptide into amino acids dipeptide + H2O ---> aminoacid + amino acid

74 10. Polypeptide (protein)
composed of three or more amino acids linked by synthesis reactions Examples of proteins include insulin, hemoglobin, and enzymes. ** There are an extremely large number of different proteins. The bases for variability include differences in the number, kinds and sequences of amino acids in the proteins

75 10. Polypeptide (protein)
composed of ____________amino acids linked by synthesis reactions Examples of proteins include _____________________________ ** There are an extremely large number of different proteins. The bases for variability include differences in the __________, kinds and _____________ of amino acids in the proteins

76 Lipids: Fats & Oils

77 Concentrated energy molecules
Lipids Concentrated energy molecules

78 Lipids Examples fats oils waxes hormones sex hormones
testosterone (male) estrogen (female)

79 Lipids Function: energy storage cell membrane cushions organs
very concentrated twice the energy as carbohydrates! cell membrane cushions organs insulates body think whale blubber!

80 Other lipids in biology
Cell membranes are made out of lipids phospholipids heads are on the outside touching water “like” water tails are on inside away from water “scared” of water forms a barrier between the cell & the outside

81 Saturated vs. unsaturated

82 B. Lipids (Fats) Fats, oils, waxes, steroids
Chiefly function in energy storage, protection, and insulation Contain carbon, hydrogen, and oxygen but the H:O is not in a 2:1 ratio Tend to be large molecules -- an example of a neutral lipid is below

83 Structure of Fat not a chain (polymer) = just a “big fat molecule”

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89 5. Neutral lipids are formed from the union of
one glycerol molecule and 3 fatty acids fatty acids + glycerol ----> neutral fat (lipid) 7. Fats -- found chiefly in animals 8. Oils and waxes -- found chiefly in plants Oils are liquid at room temperature, waxes are solids 10. Lipids along with proteins are key components of cell membranes 11. Steroids are special lipids used to build many reproductive hormones and cholesterol

90 Proteins are very versatile!
They play different roles in the body Some act as hormones Some as enzymes to do chemical reactions A Enzyme B Some as antibodies to protect you Some act as hemoglobin to help carry oxygen

91 Many Functions of Membrane Proteins
“Channel” Outside Plasma membrane Inside Transporter Enzyme activity Cell surface receptor “Antigen” Signal transduction - transmitting a signal from outside the cell to the cell nucleus, like receiving a hormone which triggers a receptor on the inside of the cell that then signals to the nucleus that a protein must be made. Cell surface identity marker Cell adhesion Attachment to the cytoskeleton

92 How proteins help in your metabolism?
By playing the role of enzymes

93 Thousands of chemical reactions happen inside each cell
Cellular respiration, photosynthesis, synthesis of proteins etc etc… Some are breakdown reactions (catabolic) and some are synthesis reactions (anabolic) Sum of all chemical reactions is called metabolism

94 CATALYST- helps speed up things without changing itself
7. Enzymes are very specific Meaning one type of enzyme catalyzes only one type of chemical reaction 6. Names end in -ase

95 CATALYST- helps speed up things without changing itself
7. Enzymes are very specific Meaning one type of enzyme catalyzes only one type of chemical reaction 6. Names end in -ase

96 How do enzymes work? Because of their SHAPE

97 How do enzymes work? Mechanism..
Lock and key How are these 2 reactions different?

98 https://www. johnbowne. org/apps/pages/index. jsp
Chin Video 1,2 Show #2 first #1

99 Anabolic reaction/synthesis

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105 How do enzymes speed up a chemical reaction?
By lowering the activation energy required for the reaction

106 What are the factors affecting enzyme activity?

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108 How does temperature affect enzyme activity?

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110 Low Temperature: Enzyme activity slow
Optimum temperature: Maximum enzyme activity High Temperature: Enzyme activity decreases because enzymes DENATURE

111 How does pH affect enzyme activity?
These 3 enzymes work at different pH Acidic pH Alkaline/basic pH

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117 Proteins as antibodies

118 Proteins as hormones

119 Enzymes

120 Enzyme action

121 Enzyme worksheets

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125 End Products Substrate Active-site Enzyme

126 Proteins Function: many, many functions hormones movement
signals from one body system to another insulin movement muscle immune system protect against germs enzymes help chemical reactions


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