1. Bellwork: 1/11 Put your phone up  Week 1/7-1/11
How do you think DNA replicates?
Why does DNA need to duplicate itself?
What type of bonds hold the nitrogenous base pairs together?

2. Today:
Finish DNA Paper Model
Unit 5, pt. 3 Notes
Review

3. Materials
Unit Book
DNA Model

4. This Week: Monday: DNA Video
Tuesday: Finish Video, Unit 5 pt. 1 & 2 Notes, Start DNA Model
Wednesday: DNA Model
Friday: Pt. 3 Notes & Review

5. Next Week: Monday: DNA Lab Tuesday: DNA Packet
Wednesday: Quiz, Unit 5 pt. 4 Notes
Friday: Finish Notes, Review, Packet

6. Homework

7. DNA Paper Model Color & cut carefully Build model
Get checked by me BEFORE you glue/tape
Tape model to other classmates’ model
Complete questions…in complete sentences
PROJECT GRADE!!!

8. Unit V: Molecular Genetics

9. Part III: DNA Replication

10. Quick Review A pairs with T C pairs with G
Hydrogen bonds hold the bases together
One DNA molecule = two strands
Antiparallel (opposite)

11. Key Factors
Replication Forks: sites where separation & replication of DNA occur
DNA Polymerase:
Joins nucleotides to produce new DNA molecule
“Proofreads” each new strand to make sure that each new strand of DNA is identical to the original

12. What is DNA Replication?
A process where DNA is copied
In what phase of Interphase is DNA replicated?

13. When? DNA replication occurs during the S phase in Interphase
Is interphase apart of mitosis?

14. Where? In eukaryotes, DNA replication occurs in the NUCLEUS
In prokaryotes, DNA replication occurs in the CYTOPLASM

15. Steps of DNA Replication

16. Step 1 DNA helicase “unzips” the DNA molecule into two strands
Breaks the Hydrogen bonds between the nitrogenous bases
Forms replication fork

17. Step 2
Each separated strand now serves as a template to produce new strands!
Primase = enzyme that acts as the “green light” for replication to start

18. Step 3 3. DNA Polymerase attaches to the single strands
Help make two new DNA strands by base pairing
A-T, G-C
New double strands of DNA are IDENTICAL

19. Step 4 4. DNA Ligase ”glues” the new DNA molecules together
Forms Hydrogen bonds between the nitrogenous bases

20. Results In… 2 IDENTICAL DNA molecules
Each molecule is made up of one old strand and one new strand

22. Review

23. What macromolecule is DNA?

24. DNA is a chain of _________________

25. What 3 things make up a nucleotide?

26. What makes up the DNA backbone?

27. What makes up the DNA backbone?

28. What are the 4 bases in DNA?

29. What bases pair together?

30. What bonds hold base pairs together?

31. What is the shape of DNA called?

32. Who got credit for discovering the shape of DNA?

33. Who took xray images of DNA?

34. Where is DNA found in eukaryotic cells?

35. Exit ?s What enzyme is responsible for unzipping the DNA strands?
What enzyme is responsible for reforming the hydrogen bonds between the bases in the new DNA strands?
What enzyme uses base pairing to help make new DNA strands?