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New pathways for itching in patients with atopic dermatitis?

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Presentation on theme: "New pathways for itching in patients with atopic dermatitis?"— Presentation transcript:

1 New pathways for itching in patients with atopic dermatitis?
Jennifer Heimall, MD, Jonathan M. Spergel, MD, PhD  Journal of Allergy and Clinical Immunology  Volume 140, Issue 2, Pages (August 2017) DOI: /j.jaci Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions

2 Fig 1 Pathways of itch sensation. The figure depicts 3 novel pathways of itching: (1) substance P–mediated activation of Mas-related G protein–coupled receptors (Mrgprs); (2) activation of GABA pathway; and (3) activation of TRPV4 receptor on the skin. Journal of Allergy and Clinical Immunology  , DOI: ( /j.jaci ) Copyright © 2017 American Academy of Allergy, Asthma & Immunology Terms and Conditions


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