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Silencing of Keap1 reduced the expression of inflammatory markers in ConA-injected livers.
Silencing of Keap1 reduced the expression of inflammatory markers in ConA-injected livers. Analysis of inflammatory markers in liver samples from luciferase siRNA (siLuc) or Keap1 siRNA (siKeap1) mice after 4 and 8 hours of ConA treatment (n=4–6 animals per condition). (A,B) mRNA levels of the indicated cytokines and pro-inflammatory markers determined by real-time PCR. Data are presented as mean±s.e.m. relative to siLuc mice. *P<0.05, **P<0.01 and ***P<0.005, siKeap1 versus siLuc. Águeda González-Rodríguez et al. Dis. Model. Mech. 2014;7: © Published by The Company of Biologists Ltd
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