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Maximum mean (SE) per cent change in serum urate from baseline (Emax) following once-daily oral administration of varying verinurad doses in combination with allopurinol 300 mg versus allopurinol 300 mg once daily, 600 mg once daily or 300 mg twice daily alone (allopurinol data pooled across cohorts). Maximum mean (SE) per cent change in serum urate from baseline (Emax) following once-daily oral administration of varying verinurad doses in combination with allopurinol 300 mg versus allopurinol 300 mg once daily, 600 mg once daily or 300 mg twice daily alone (allopurinol data pooled across cohorts). Roy Fleischmann et al. RMD Open 2018;4:e000584 Copyright © BMJ Publishing Group & EULAR. All rights reserved.
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