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A randomized, double-blind trial of the effect of treatment with montelukast on bronchial hyperresponsiveness and serum eosinophilic cationic protein.

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Presentation on theme: "A randomized, double-blind trial of the effect of treatment with montelukast on bronchial hyperresponsiveness and serum eosinophilic cationic protein."— Presentation transcript:

1 A randomized, double-blind trial of the effect of treatment with montelukast on bronchial hyperresponsiveness and serum eosinophilic cationic protein (ECP), soluble interleukin 2 receptor (sIL-2R), IL-4, and soluble intercellular adhesion molecule 1 (sICAM-1) in children with asthma  Iwona Stelmach, MD, PhDa, Joanna Jerzynska, MDa, Piotr Kuna, MD, PhD, Profb  Journal of Allergy and Clinical Immunology  Volume 109, Issue 2, Pages (February 2002) DOI: /mai Copyright © 2002 Mosby, Inc. Terms and Conditions

2 Fig. 1 Serum sICAM-1 levels (ng/mL) before and after treatment with montelukast (left panel ) and placebo (right panel ). The symbol — indicates mean value. p 1, Changes from baseline within each group; p 2, changes between groups before treatment; p 3, changes between groups after treatment. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2002 Mosby, Inc. Terms and Conditions

3 Fig. 2 Serum ECP levels (μg/L) before and after treatment with montelukast (left panel ) and placebo (right panel ). The symbol — indicates mean value. p 1, Changes from baseline within each group; p 2, changes between groups before treatment; p 3, changes between groups after treatment. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2002 Mosby, Inc. Terms and Conditions

4 Fig. 3 FEV1 (percentage of predictive value) before and after treatment in montelukast (left panel ) and placebo group (right panel ). The symbol — indicates mean value. p 1, Changes from baseline within each group; p 2, changes between groups before treatment; p 3, changes between groups after treatment. Journal of Allergy and Clinical Immunology  , DOI: ( /mai ) Copyright © 2002 Mosby, Inc. Terms and Conditions

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