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Volume 8, Issue 4, Pages (August 2002)

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Presentation on theme: "Volume 8, Issue 4, Pages (August 2002)"— Presentation transcript:

1 Volume 8, Issue 4, Pages 269-273 (August 2002)
Protein oxidation in male Syrian hamster kidney during estrogen-induced carcinogenesis  T Stefaniak, J Krajewski, J Kobiela, W Makarewicz, A Stanek, M Asano, R Kondo, T Wakabayashi, Z Gruca, M Woźniak  Pathophysiology  Volume 8, Issue 4, Pages (August 2002) DOI: /S (02)

2 Fig. 1 Level of carbonyl groups in kidneys of hamsters throughout the estradiol administration. (Statistically significant difference in Student's t-test between the treated and control groups has been indicated as follows: * P<0.05, ** P<0.01 and *** P<0.001.) Pathophysiology 2002 8, DOI: ( /S (02) )

3 Fig. 2 Kidney weight of estrogenized and control animals presented as a percent of total body mass. (Statistically significant difference in Student's t-test between the groups * P<0.05, ** P<0.01, *** P<0.001.) Pathophysiology 2002 8, DOI: ( /S (02) )

4 Fig. 3 Testes weight in the estrogenized and control animals presented as a percent of total body mass. (Statistically significant difference in Student's t-test between the groups * P<0.05, ** P<0.01, *** P<0.001.) Pathophysiology 2002 8, DOI: ( /S (02) )

5 Fig. 4 Histopathologic images of kidneys of estrogenized hamsters: (A) arrow indicates an interstitial hyperplastic focus after 3 months of estrogenization (H+E, 400×); (B) arrow indicates a large proliferative focus surrounding a glomerulus after 6 months of estrogenization (H+E, 400×); (C) circle indicates neoplastic lesion (most probably of blastemal origin) after 9 months of estrogenization (H+E, 400×). Pathophysiology 2002 8, DOI: ( /S (02) )


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