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Volume 72, Issue 11, Pages 1301-1303 (December 2007)
Thiazolidinediones: A novel class of drugs for the prevention of diabetic nephropathy? F. Zheng, Y. Guan Kidney International Volume 72, Issue 11, Pages (December 2007) DOI: /sj.ki Copyright © 2007 International Society of Nephrology Terms and Conditions
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Figure 1 Mechanisms by which thiazolidinediones attenuate albuminuria and improve diabetic nephropathy. TNF-α, tumor necrosis factor-α; TGFβ, transforming growth factor-β; PAI-1, plasminogen activator inhibitor-1; RAS, renin–angiotensin system; ET-1, endothelin-1; FFA, free fatty acid; UAE, urinary albumin excretion. Asterisks indicate evidence from the study by Miyazaki et al.4 Kidney International , DOI: ( /sj.ki ) Copyright © 2007 International Society of Nephrology Terms and Conditions
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