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New 29-mm Balloon-Expandable Prosthesis for Transcatheter Aortic Valve Implantation in Large Annuli  Axel Unbehaun, MD, Miralem Pasic, MD, PhD, Thorsten.

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Presentation on theme: "New 29-mm Balloon-Expandable Prosthesis for Transcatheter Aortic Valve Implantation in Large Annuli  Axel Unbehaun, MD, Miralem Pasic, MD, PhD, Thorsten."— Presentation transcript:

1 New 29-mm Balloon-Expandable Prosthesis for Transcatheter Aortic Valve Implantation in Large Annuli 
Axel Unbehaun, MD, Miralem Pasic, MD, PhD, Thorsten Drews, MD, Semih Buz, MD, Stephan Dreysse, MD, Marian Kukucka, MD, Alexander Mladenow, MD, Ekaterina Ivanitskaja-Kühn, MD, Roland Hetzer, MD, PhD  The Annals of Thoracic Surgery  Volume 95, Issue 6, Pages (June 2013) DOI: /j.athoracsur Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

2 Fig 1 Assessment of device landing zone geometry. Several views are shown (from left to right): aortic annulus in double-oblique transverse view, coronal view, single-oblique sagittal view, and sinus of Valsalva in double-oblique transverse view. A schematic drawing (A) indicating where measurements were taken, an example of “female shaped” aorta (B) with protruding aortic sinus [5], and an example of “male shaped” aorta (C) with slim aortic sinus are shown. (Aan = aortic annulus area; dan coronal = coronal annulus diameter; dan sagittal = sagittal annulus diameter; daorta = diameter of ascending aorta; dLVOT = diameter of left ventricular outflow tract; dRCS, dLCS, dNCS = intercommissural distances; dSV coronal, dSV sagittal = diameters of the aortic sinus; hLCA, hRCA = perpendicular distance from annulus to coronary ostia; hSTJ = height of the aortic sinus; LCA = left coronary artery; RCA = right coronary artery.) The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

3 Fig 2 (A) Kaplan-Meier survival functions of study group (red line) and control group (blue line). The overall survival functions are given as well as (B) the survival functions for patients (pts) without cardiogenic shock. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

4 Fig 3 (A) Echocardiographic measurements of mean pressure gradient (dPmean) and (B) effective orifice area (EOA) were made preoperatively in transthoracic echocardiography, at the end of the procedure (transesophageal echocardiography), and before discharge (transthoracic echocardiography). The dashed lines indicate in vitro measured variables for the 29-mm prosthesis as specified by the manufacturer (Design Validation Test Protocol 17570, Edwards Lifesciences). The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

5 Fig 4 Regression plots and Spearman correlation between annulus diameter measurements derived from transesophageal echocardiography (abscissa: dTEE) and multislice computed tomography (ordinate: [A] dan coronal = coronal annulus diameter, [B] dan sagittal = sagittal annulus diameter, [C] dan area = annular area derived diameter, [D] dan mean = mean annulus diameter). The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur ) Copyright © 2013 The Society of Thoracic Surgeons Terms and Conditions

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