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The Missing Antibody: The Pitfalls of ANCA Testing

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Presentation on theme: "The Missing Antibody: The Pitfalls of ANCA Testing"— Presentation transcript:

1 The Missing Antibody: The Pitfalls of ANCA Testing
James Wingfield Digby, MD, MRCP, DTMH, Brendan Tinwell, MD, FRCPath, Joanna Sheldon, PhD, FRCPath, Joe Wang, MD, MRCP, PhD  The American Journal of Medicine  Volume 130, Issue 3, Pages e93-e96 (March 2017) DOI: /j.amjmed Copyright © Terms and Conditions

2 Figure 1 Chest computed tomography showing extensive bilateral patchy air space infiltrates and ground-glass changes. The American Journal of Medicine  , e93-e96DOI: ( /j.amjmed ) Copyright © Terms and Conditions

3 Figure 2 Video-assisted thoracoscopic lung biopsy (A) low-power (40×) view of lung demonstrating focal organizing pneumonia (arrow) and subtle perivascular inflammation (insert 200×) (hematoxylin & eosin stain). (B) High-power (200×) view showing coarse haemosiderin deposition within alveolar macrophages (solid arrow) and fine deposition within alveolar septa and the wall of a small blood vessel (open arrow – pulmonary hemosiderosis) (Perls stain). The American Journal of Medicine  , e93-e96DOI: ( /j.amjmed ) Copyright © Terms and Conditions

4 Figure 3 Renal biopsy showing evidence of acute necrotizing crescentic glomerulopathy (arrow) with a relatively well-preserved background interstitium (hematoxylin & eosin stain, 200×). The American Journal of Medicine  , e93-e96DOI: ( /j.amjmed ) Copyright © Terms and Conditions


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