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Published byNeal Farmer Modified over 5 years ago
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Mean (SD) AMG 557 serum concentration–time profiles following single-ascending dose (SAD) (A) and multiple-ascending dose (MAD) (B) administration AMG 557 in subjects with systemic lupus erythematosus. Mean (SD) AMG 557 serum concentration–time profiles following single-ascending dose (SAD) (A) and multiple-ascending dose (MAD) (B) administration AMG 557 in subjects with systemic lupus erythematosus. The dose levels are indicated in the legend, with the number of values per symbol in parentheses. The lower limit of quantitation (LLOQ) of 15 ng/mL is indicated as a dashed horizontal line on each graph. IV, intravenous; SC, subcutaneous. B A Sullivan et al. Lupus Sci Med 2016;3:e000146 ©2016 by Lupus Foundation of America
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