1. Cyp8b1−/− mice have an altered circulating bile acid pool.
Cyp8b1−/− mice have an altered circulating bile acid pool. A: Plasma bile acid pool in control (+/+) and Cyp8b1−/− (−/−) mice (n = 3–5). HDC, hyodeoxycholic acid. B: Hepatic transcript levels of Cyp7a1, Cyp27a1, and Cyp8b1 in control (+/+) and Cyp8b1−/− (−/−) mice (n = 4–5). Data are shown as mean ± SEM. ND, not detectable. *P < 0.05 and **P < 0.01, by Student t test.
Achint Kaur et al. Diabetes 2015;64:
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