Presentation is loading. Please wait.

Presentation is loading. Please wait.

Fate transformation and delayed neurogenesis in distinct diencephalic domains in the Ascl1KO mouse embryos. Fate transformation and delayed neurogenesis.

Published byÁngela Soto Modified over 5 years ago

Similar presentations

Presentation on theme: "Fate transformation and delayed neurogenesis in distinct diencephalic domains in the Ascl1KO mouse embryos. Fate transformation and delayed neurogenesis."— Presentation transcript:

1 Fate transformation and delayed neurogenesis in distinct diencephalic domains in the Ascl1KO mouse embryos. Fate transformation and delayed neurogenesis in distinct diencephalic domains in the Ascl1KO mouse embryos. (A-J) ISH with Gad1, Helt, Slc17a6, Ngn2 and Gata2 probes on WT and Ascl1KO diencephalon at E12.5. (K,L) Gata2 and Gata3 co-IHC on WT and Ascl1KO diencephalon at E12.5. (M-P) Sox2 and HuC/D co-IHC on WT and Ascl1KO diencephalon at E12.5 (M,N) and E13.5 (O,P). Close-up from P2-P3 region is presented in M-P. Arrows in B, F and H indicate the region where the fate transformation is most apparent; in J and L the downregulation of Gata2 and Gata3 in P1; and in N the aberrant upregulation of HuC/D in the pTh-R region. Dotted lines indicate the prosomere boundaries. Scale bars: 100 μm. Sini-Maaria Virolainen et al. Development 2012;139: © Published by The Company of Biologists Ltd

Download ppt "Fate transformation and delayed neurogenesis in distinct diencephalic domains in the Ascl1KO mouse embryos. Fate transformation and delayed neurogenesis."

Similar presentations

Mitochondria localize to both the front and the rear of neutrophils.

Mitochondria localize to both the front and the rear of neutrophils.
Identification of vegetally localised vrtn transcripts.

Identification of vegetally localised vrtn transcripts.
The neuroepithelium of mid-neurulation mammalian embryos displays planar-polarised F-actin profiles. The neuroepithelium of mid-neurulation mammalian embryos.

The neuroepithelium of mid-neurulation mammalian embryos displays planar-polarised F-actin profiles. The neuroepithelium of mid-neurulation mammalian embryos.
Scanning electron microscopy analysis of EGK-I to -V chick embryos.

Scanning electron microscopy analysis of EGK-I to -V chick embryos.
CK2 is required for early cell divisions in C. elegans embryos

CK2 is required for early cell divisions in C. elegans embryos
Effect of cxcr3.2 mutation on dissemination of local mycobacterial infection within 24 hpi. Effect of cxcr3.2 mutation on dissemination of local mycobacterial.

Effect of cxcr3.2 mutation on dissemination of local mycobacterial infection within 24 hpi. Effect of cxcr3.2 mutation on dissemination of local mycobacterial.
Fig. 7. Vinculin recruitment enhances the efficiency of barrier formation.(A) TER measurements after a calcium switch in α-catenin-depleted MDCK cells.

Fig. 7. Vinculin recruitment enhances the efficiency of barrier formation.(A) TER measurements after a calcium switch in α-catenin-depleted MDCK cells.
Fig. 2. Morphological changes of cultured adherent fibroblastic cells after OA treatment related to actin microfilament reorganization.(A) Cells observed.

Fig. 2. Morphological changes of cultured adherent fibroblastic cells after OA treatment related to actin microfilament reorganization.(A) Cells observed.
Nephrogenesis in vitro can be rescued in 3D co-cultures by siRNA treatment of Renca cells. Nephrogenesis in vitro can be rescued in 3D co-cultures by siRNA.

Nephrogenesis in vitro can be rescued in 3D co-cultures by siRNA treatment of Renca cells. Nephrogenesis in vitro can be rescued in 3D co-cultures by siRNA.
A highly conserved six-amino-acid region in the C-terminal CT domain of MARCH8 is responsible for its ability to downregulate TfR. A highly conserved six-amino-acid.

A highly conserved six-amino-acid region in the C-terminal CT domain of MARCH8 is responsible for its ability to downregulate TfR. A highly conserved six-amino-acid.
Dany is required for normal spermatogenesis to proceed beyond the spermatocyte stage. dany is required for normal spermatogenesis to proceed beyond the.

Dany is required for normal spermatogenesis to proceed beyond the spermatocyte stage. dany is required for normal spermatogenesis to proceed beyond the.
Altered oligodendrocyte progenitor cell (OPC) marker protein expression in two white matter regions of ShhΔFP/ΔFP and SmoΔNT/ΔNT embryos at E15.5. Altered.

Altered oligodendrocyte progenitor cell (OPC) marker protein expression in two white matter regions of ShhΔFP/ΔFP and SmoΔNT/ΔNT embryos at E15.5. Altered.
Fig. 6. Cross-section of the stomach wall and spiral intestine of the embryo, stained with PAS. (A) Surface of the stomach wall (SW) and ingested material.

Fig. 6. Cross-section of the stomach wall and spiral intestine of the embryo, stained with PAS. (A) Surface of the stomach wall (SW) and ingested material.
Fig. 6. The cholinergic receptor subunits a6 (Chrna6) and b3 (Chrnb3) are (subset) specifically expressed in mdDA neurons during development.(A) The Chrna6.

Fig. 6. The cholinergic receptor subunits a6 (Chrna6) and b3 (Chrnb3) are (subset) specifically expressed in mdDA neurons during development.(A) The Chrna6.
The C-terminal membrane-proximal region of MARCH8 interacts with TfR.

The C-terminal membrane-proximal region of MARCH8 interacts with TfR.
Expression of Shh-Gli target genes in astrocyte progenitors.

Expression of Shh-Gli target genes in astrocyte progenitors.
Embryonic corneal defects in E18.5 AP-2β NCC KO mutant embryos.

Embryonic corneal defects in E18.5 AP-2β NCC KO mutant embryos.
Altered progenitor domain marker protein expression in ShhΔFP/ΔFP embryos at E12.5. Altered progenitor domain marker protein expression in ShhΔFP/ΔFP embryos.

Altered progenitor domain marker protein expression in ShhΔFP/ΔFP embryos at E12.5. Altered progenitor domain marker protein expression in ShhΔFP/ΔFP embryos.
Neutralization and knockdown of TGFβ2 results in fewer nephrons ex vivo. Neutralization and knockdown of TGFβ2 results in fewer nephrons ex vivo. (A,B)

Neutralization and knockdown of TGFβ2 results in fewer nephrons ex vivo. Neutralization and knockdown of TGFβ2 results in fewer nephrons ex vivo. (A,B)
Scanning EM shows cilia abnormalities in the neural tube.

Scanning EM shows cilia abnormalities in the neural tube.

Similar presentations

Ads by Google