1. HoxA9 directly regulates cell cycle control genes.
HoxA9 directly regulates cell cycle control genes. (A) Genomic environment, HoxA9 binding, RNA production, and H3K27ac status of cyclin-dependent kinase 6 (Cdk6), cyclin D1 (Ccnd1), and telomerase RNA component (Terc) loci. The line graph shows transcription rates of these genes in response to HoxA9 activity. (B) Core pathways of transformation by HoxA9.
Xiaoxia Zhong et al. Blood Adv 2018;2:
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